Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Reperfusion injury
ADR ID BADD_A06206
ADR Hierarchy
12      Injury, poisoning and procedural complications
12.02      Procedural related injuries and complications NEC
12.02.01      Cardiac and vascular procedural complications
12.02.01.003      Reperfusion injury
24      Vascular disorders
24.03      Vascular disorders NEC
24.03.02      Non-site specific vascular disorders NEC
24.03.02.012      Reperfusion injury
Description Adverse functional, metabolic, or structural changes in ischemic tissues resulting from the restoration of blood flow to the tissue (REPERFUSION), including swelling; HEMORRHAGE; NECROSIS; and damage from FREE RADICALS. The most common instance is MYOCARDIAL REPERFUSION INJURY. [MeSH]
MedDRA Code 10063837
MeSH ID D015427; D054318; D015427
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
No-reflow phenomenon | Reperfusion injury | Slow reflow phenomenon | Reperfusion Injury | Reperfusion Damage | Damage, Reperfusion | Damages, Reperfusion | Reperfusion Damages | Ischemia-Reperfusion Injury | Ischemia Reperfusion Injury | Injury, Ischemia-Reperfusion | Injuries, Ischemia-Reperfusion | Injury, Ischemia Reperfusion | Ischemia-Reperfusion Injuries | Injury, Reperfusion | Injuries, Reperfusion | Reperfusion Injuries
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
Intercellular adhesion molecule 1P05362T26203
MyeloperoxidaseP05164T23471
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00279Bivalirudin0.000097%
BADD_D01507Mycophenolate mofetil0.000341%
BADD_D02438Enoxaparin0.000274%
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